Service Capabilities

Service Capabilities

Molecular Imaging and Analysis

We use molecular imaging techniques such as PET-CT and MRI to scan large animals and accurately obtain pharmacokinetic parameters in vivo. We provide not only the real-time and continuous assessment of disease animal models for diagnosis, disease progression monitoring, and treatment efficacy evaluation, thereby obtaining pharmacodynamic data, but also technical services for new drug development, including molecular radiolabeling synthesis and evaluation of drug targeting and tumor targeting therapeutic effects through animal imaging analysis.

  • Brain MR And PET imaging of
    monkeys (tracer: 18F-FDG)

  • Whole body PET/CT dynamic imaging of
    monkeys

Services Scope
⑴ Radiolabeling and Molecular Probe Synthesis: Including isotopes such as124I、89Zr、64Cu、68Ga、18F,etc.
⑵ Image Acquisition and Data Analysis: PET/CT image acquisition, MRI/fMRI image acquisition and analysis, PET/MRI image fusion, SUV/SUVR analysis, etc.
⑶ Application Scope: PK/PD, ADME, dose range testing, and safety evaluation; assessment of disease animal models, investigation of disease mechanisms; evaluation of drug targeting, etc.
  • MRI3.0 imaging system of large animals

    uMR 770

  • PET/CT in vivo imaging system of large animals

    uBio EXPLORER

Advantages

  • In vivo imaging, dynamic quantification, self-control, and continuous observation.

  • Through dynamic studies on living animals, precise pharmacokinetic and pharmacodynamic data can be obtained, reflecting a visual representation of the absorption, distribution, metabolism, and excretion processes of drugs within biological organisms.

Application in Four Major Fields

  • Drug Safety Evaluation

    To detect the toxicity of drugs to the body

  • Biological Validation

    To study the distribution of drugs

  • Pharmacokinetics

    To obtain pharmacokinetic parameter

  • Pharmacological Validation and Pharmacodynamic Evaluation

    To reflect the extent to which receptors are occupied by drugs, the affinity of drugs to receptors, and the biological activity of drug responses to receptors.