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Cynomolgus monkey of metabolic dysfunction-associated steatotic liver disease (MASLD)

4/30/2024 12:48:11 PM | Visits:156

1. The HE staining of liver tissue showed fatty degeneration at 3 months after modeling.


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     Figure 1. The HE staining of liver tissue in cynomolgus monkey with non-acoholic Fatty Liver.

2. The HE staining showed fat vacuolization and extensive infiltration of inflammatory cells at 5-6 months after modeling.

                        

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     Figure 2. The HE staining of liver tissue in cynomolgus monkey with non-alcoholic Steatohepatitis.


3. The VG staining of liver tissue showed destruction of lobular structure and formation of fibrous septa at 8-9 months after modeling.


    Figure 3. The VG staining of liver tissue in cynomolgus monkey with non-alcoholic liver fibrosis.